Maybe I'm oversimplifying this, but to me this game comes down to Jordan McCloud. Fast QBs can screw up a defense, so it's crucial that the front 7 gets pressure and that Delontae Scott, Turner Coxe, Tyeson Neals and the rest keep McCloud in the pocket. Make him beat you though the air and SMU wins. Let him get loose as a runner and it's anyone's guess.
My money is on Kevin Kane.